diff --git a/ale_linters/c/clang.vim b/ale_linters/c/clang.vim
index 7680305..25d9371 100644
--- a/ale_linters/c/clang.vim
+++ b/ale_linters/c/clang.vim
@@ -3,20 +3,27 @@
 
 call ale#Set('c_clang_executable', 'clang')
 call ale#Set('c_clang_options', '-std=c11 -Wall')
+call ale#Set('c_gcc_parse_makefile', 0)
 
 function! ale_linters#c#clang#GetExecutable(buffer) abort
     return ale#Var(a:buffer, 'c_clang_executable')
 endfunction
 
 function! ale_linters#c#clang#GetCommand(buffer) abort
-    let l:paths = ale#c#FindLocalHeaderPaths(a:buffer)
+let l:cflags = []
+    if g:ale_c_parse_makefile
+        let l:cflags = join(ale#c#ParseMakefile(a:buffer), ' ')
+    endif
+    if empty(l:cflags)
+        let l:cflags = ale#c#IncludeOptions(ale#c#FindLocalHeaderPaths(a:buffer))
+    endif
 
     " -iquote with the directory the file is in makes #include work for
     "  headers in the same directory.
     return ale#Escape(ale_linters#c#clang#GetExecutable(a:buffer))
     \   . ' -S -x c -fsyntax-only '
     \   . '-iquote ' . ale#Escape(fnamemodify(bufname(a:buffer), ':p:h')) . ' '
-    \   . ale#c#IncludeOptions(l:paths)
+    \   . l:cflags . ' '
     \   . ale#Var(a:buffer, 'c_clang_options') . ' -'
 endfunction
 
diff --git a/ale_linters/c/gcc.vim b/ale_linters/c/gcc.vim
index 4b241e3..3ad243a 100644
--- a/ale_linters/c/gcc.vim
+++ b/ale_linters/c/gcc.vim
@@ -3,20 +3,27 @@
 
 call ale#Set('c_gcc_executable', 'gcc')
 call ale#Set('c_gcc_options', '-std=c11 -Wall')
+call ale#Set('c_parse_makefile', 0)
 
 function! ale_linters#c#gcc#GetExecutable(buffer) abort
     return ale#Var(a:buffer, 'c_gcc_executable')
 endfunction
 
 function! ale_linters#c#gcc#GetCommand(buffer) abort
-    let l:paths = ale#c#FindLocalHeaderPaths(a:buffer)
+    let l:cflags = []
+    if g:ale_c_parse_makefile
+        let l:cflags = join(ale#c#ParseMakefile(a:buffer), ' ')
+    endif
+    if empty(l:cflags)
+        let l:cflags = ale#c#IncludeOptions(ale#c#FindLocalHeaderPaths(a:buffer))
+    endif
 
     " -iquote with the directory the file is in makes #include work for
     "  headers in the same directory.
     return ale#Escape(ale_linters#c#gcc#GetExecutable(a:buffer))
     \   . ' -S -x c -fsyntax-only '
     \   . '-iquote ' . ale#Escape(fnamemodify(bufname(a:buffer), ':p:h')) . ' '
-    \   . ale#c#IncludeOptions(l:paths)
+    \   . l:cflags . ' '
     \   . ale#Var(a:buffer, 'c_gcc_options') . ' -'
 endfunction
 
diff --git a/autoload/ale/c.vim b/autoload/ale/c.vim
index f6ad7de..4bf8ad4 100644
--- a/autoload/ale/c.vim
+++ b/autoload/ale/c.vim
@@ -22,6 +22,69 @@ function! ale#c#FindProjectRoot(buffer) abort
     return ''
 endfunction
 
+function! ale#c#ParseCFlags(project_root, stdout_make) abort
+    let l:cflags_list = []
+    let l:cflags = split(a:stdout_make, " ")
+    let l:shell_option = 0
+    let l:macro_option = 0
+    let l:previous_option = ''
+    for l:option in l:cflags
+        " Check if cflag contained spaces
+        if l:shell_option || stridx(l:option, "=`") >= 0
+            " Cflag contained shell command with spaces (ex. -D='date +%s')
+            let l:shell_option = 1
+            let l:previous_option .= l:option . ' '
+            if l:option[-1: -1] != "`"
+                continue
+            endif
+            let l:shell_option = 0
+        elseif l:macro_option || stridx(l:option, "$((") > 0
+            " Cflag contained macro with spaces (ex -Da=$(( 4 * 20  )))
+            let l:macro_option = 1
+            let l:previous_option .= l:option . ' '
+            if stridx(l:option, "))") < 0
+                continue
+            endif
+            let l:macro_option = 0
+        endif
+        if l:previous_option != ''
+            let l:option = l:previous_option
+            let l:previous_option = ''
+        endif
+        " Fix relative paths if needed
+        if stridx(l:option, "-I") >= 0
+            if stridx(l:option, "-I/") < 0
+                let l:option = '-I' . a:project_root . s:sep . l:option[2:]
+            endif
+        endif
+        " Parse the cflag
+        if stridx(l:option, "-I") >= 0 ||
+           \ stridx(l:option, "-D") >= 0
+            if index(l:cflags_list, l:option) < 0
+                call add(l:cflags_list, l:option)
+            endif
+        endif
+    endfor
+    return l:cflags_list
+endfunction
+
+function! ale#c#ParseMakefile(buffer) abort
+    let l:project_root = ale#c#FindProjectRoot(a:buffer)
+    let l:project_cflags = []
+
+    if !empty(l:project_root)
+        if !empty(globpath(l:project_root, 'Makefile', 0))
+            let stdout_make = system('cd '. l:project_root . ' && make -n')
+             for l:object in split(l:stdout_make, '\n')
+                 if stridx(l:object, expand("%t"))
+                     return ale#c#ParseCFlags(l:project_root, l:object)
+                 endif
+             endfor
+        endif
+    endif
+    return []
+endfunction
+
 " Given a buffer number, search for a project root, and output a List
 " of directories to include based on some heuristics.
 "